Friday, 14 June 2013

Scientist in Noni Research


Dr. Gary Tran

Country of OriginVietnam
Education and Professional ExperienceDr. Gary Tran is a 1964 graduate of Oklahoma State University College of Veterinary Medicine. After 12 years of academic work in his native country of Vietnam, he has been doing small animal practice in Louisville since 1976, then emergency and trauma medicine since 1986. During that time he has performed more than 14,000 surgical procedures of all types and treated some 78,000 cases. Dr. Gary Tran is one of the new breed of veterinarian who combines traditional veterinary medicine and alternative veterinary medicine to treat a great variety of puzzling small animal diseases with rewarding success.
Link to Noni Research
He is fascinated with the health benefits of alternative medicine and nutritional supplements.  He has conducted initial research on noni usage to improve the health of animals.
Location/ HometownLouisville, Kentucky



Dr. Eiichi Furusawa

Country of Origin
Japan
Education and Professional ExperienceDoctor of Medicine (M.D.) from Osaka University, Japan
Research Associate, Research Institute for Microbial Diseases, Osaka University
Fellow in Experimental Therapeutics, Department of Medical Microbiology, Stanford University
Fellow, Department of Microbiology, Columbia University
Research Associate, Laboratory of Experimental Therapeutics, Department of Medical Microbiology, Stanford University
Associate Pharmacologist, Pacific Biomedical Center, University of Hawaii
Associate Professor of Pharmacology, School of Medicine, University of Hawaii
Professor of Pharmacology, School of Medicine, University of Hawaii
Publications
Dr. Furusawa has published numerous research studies in many scientific and medical journals.  The following noni research which he has published involves studying the antitumor substances found within noni.
  1. Hirazumi, E. Furusawa, S.C. SHou, and C. Ching.  Antitumor activity of Morinda citrifolia on intraperitoneally implanted Lewis lung carcinoma in mice.  The 83rd Annual Meeting of American Association of Cancer Research.  May 1992, San Diego.
  2. A. Hirazumi, E. Furusawa, S.C. Chou.  Antitumor activities of Morinda citrifolia (Noni) on intraperitoneally implanted Lewis lung carcinoma and Rauscher leukemia in mice.  American College of Physicians, Hawaii Scientific Meeting, March 11-12, 1993.  Abstract #24.
  3. A. Hirazumi, E. Furusawa, S.C. Chou and Y. Hokama.  Antitumor activity of Morinda citrifolia (Noni) on intraperitoneally implanted Lewis lung carcinoma.  Annual meeting of Western Pharmacology Society on 1/30-2/4, 1994 at Kona, Hawaii.  Abstract.
  4. A. Hirazumi, E. Furusawa, S.C. Chou and Y.Hokama.  Antitumor activity of Morinda citrifolia (Noni) on intraperitoneally implanted Lewis lung carcinoma.  American College of Physicians Hawaiian Scientific Meeting on 3/24-2/25, 1994 at Honolulu, Hawaii.  Abstract.
  5. A. Hirazumi, E. Furusawa, S.C. Chou and Y. Hokama.  Anticancer activity of Morinda citrifolia (Noni) on intraperitoneally implanted Lewis lung carcinoma in syngeneic mice.  Proceedings Western Pharmacological Society: 37, 145-146, 1994.
  6. A. Hirazumi, E. Furusawa, S.C. Chou and Y. Hokama.  Anticancer activity of Morinda citrifolia (Noni) on intraperitoneally implanted Lewis lung carcinoma and retroviral leukemia in mice.  The 85th annual meeting of American Association for Cancer Research (AACR) on 4/10-4/13, 1994 at San Francisco, CA.  Abstract.
  7. A. Hirazumi, E. Furusawa, S.C. Chou and Y. Hokama.  Anticancer activity of Morinda citrifolia (Noni) against Lewis lung carcinoma and Rauscher retroviral leukemia in mice.  Annual meeting of Federation of American society for Exp. Biol. in April, 1995 at Atlanta, GA.  Abstract.
  8. A. Hirazumi, E. Furusawa, S.C. Chou and Y. Hokama.  Immunomodulation contributes to the anticancer activity of Morinda citrifolia (Noni) fruit juice.  Annual meeting of Western Pharmacology Society on 1/27-2/1, 1996 at Lake Tahoe, CA.  Abstract.
  9. A. Hirazumi, E. Furusawa, S.C. Chou and Y. Hokama.  Immunomodulation contributes to the anticancer activity of Morinda citrifolia (Noni) fruit juice.  Proceedings of the Western Pharmacological Socity: 38, 5-7, 1996.
  10. A. Hirazumi and E. Furusawa.  Isolation of an antitumor agent from the fruit juice of Morinda citrifolia (Noni).  Submitted to Patent & Copyright Committee of University of Hawaii and obtained application-right for patent, Sept. 1997.
  11. A. Hirazumi and E. Furusawa.  An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia (Noni) with antitumor activity.  Phytotherapy Research: 13, 380-387, 1999.
  12. E. Furusawa, A. Hirqzumi, S. Story and J. Jensen.  Antitumor potential of polysaccharide-rich substance from the fruit juice of Morinda citrifolia (Noni) on sarcoma 180 ascites tumor in mice.  Phytotherapy Research: 17, 1158-1164, 2003.

Noni Motivation
"From our 12 years repeated-experiment in University of Hawaii using scientific technology on noni juice…it is naturally expected that noni juice might be beneficial to treat and/ or prevent human cancers by enhancing the anticancer immune systems inhuman body just as that in mice."
Location/ HometownHonolulu, Hawaii



Dr. Luis David Lemus Acuña

Country of OriginChile
Education and Professional Experience
Professional Degree from the Veterinary Medical (VMD), University of Chile
Academic Degree from the Doctor Vet Science, Madrid University, Spain
After completing his educational degrees, Dr. Lemus professional experience has devoted his efforts to furthering science and medicine as the Director of Morphology at the University of Chile, where he later became a Full Professor or Histology and Embryology.
Accomplishments
Professor invited University of Madrid, 1982, 1988
Foreign Academic Member of Real Academy of Vet., Spain Institute, 1988
Awards
HWO Fellowship, Complutense University of Madrid, 1974-1975
Award to the Best Thesis to obtain the Doctor Degree in Veterinary Sc. (Cum Laude,) Hispanic Culture Institute, 1975
Recent Publications
D. Lemus et al. Effect of Morinda citrofolia (Tahitian Noni Juice, TNJ) on angiogenesis and tumor growth in carrier mice of tumor TA3-MTX-R. (Phytotherapy Research), May 2004.
M. Molina, V. Ferreira, C. Valk, J. Orellana, A. Rojas, R. Billeta, D. Lemus, A. Ferreira (2004). An in vivo role for Trypanosoma cruzi calreticulin in antiangiogenesis. Sent to Mol. Biochem. Parasitol.
J.P. Castillo, M. Fuenzalida, D. Lemus, A. Guerrero (2003) Actividad antineoplásica y antimestásica de la asociación de betametasona, sulindac y oxytetraciclina. Rev. Chil Cancerología Y Hematología Vol 13: 41-48.
J.Zúñiga, M.Fuenzalida, A.Guerrero, J.Illanes, A.Dabancens, E.Díaz and D.Lemus (2003) Effects of steroidal and non steroidal drugs on the neovascularization response induced by tumoral TA3 supernatant on CAM from chick embryo. Biol Res  36 :233-240.
J.Illanes, A.Dabancens, O.Acuña, M.Fuenzalida,A.Guerrero, C.López and D.Lemus (2002). Effects of betamethasone, sulindac and quinacrine drugs on the inflammatory neoangiogenesis response induced by polyurethane sponge implantes in mouse. Biol. Res. 35: 339-343, 2002.
L.Strauss, M.Fuenzalida, J.Illanes, A.Dabancens, E.Díaz, A.Guerrero and D.lemus (2002). Effect of sulfated -cyclodextrin, a water soluble cycloamylose, on the promotion and/or inhibition of angiogenesis. Pathol. Oncol. Res. Vol 8, 1:47-53.
D. Lemus, A. Dabancens, J. Illanes, M. Fuenzalida, A. Guerrero y P. Gonzalez (2001).  "Antiangiogenesis effect of betamethasone on the chick CAM stimulated by TA3 tumor supernatant".  Biol. Res 34:227-236.
Guerrero,A., Dabancens,A., Zipper,J., Lemus,D. (1999) Regresión de tumor transplantable mediante la administración de quinacrina mas indometacina oral en raton AJ. Rev.Chil.Citol.Vol.3:20-23.
Guerrero,A., Diaz-Muñoz,C., Dabancens,A., Lemus,D., Fuenzalida,M., Illanes,J., Zipper,J. (1998) Actividad antineoplásica y antimestásica de la quinacrina en combinación co ketoprofeno, betametasona y levamisol en tumores  TA3 transplantables de ratón. Rev.Chil.Cancerol. y hematol.8:169-176.
Location/ Hometown
Chile



Dr. Chi-Tang Ho

Education and Professional ExperienceBS, Chemistry, National Taiwan University 
MA, Organic Chemistry, Washington University 
PhD, Organic Chemistry, Washington University
Dr. Chi Tang Ho received his PhD in Organic Chemistry in 1974 and immediately started working professionally as a researcher and professor in the Food Science Department at Rutgers University. He is now Director of the food science graduate program at Rutgers University in New Jersey.
Accomplishments
Dr. Ho has written over 140 book chapters on different topics related to science and nutrition. Additionally he has received 5 U.S. patents related to nutrition. He has been an associate editor for the Journal of Food Science, and served on the editorial boards of many food industry publications. He is currently the senior editor at Molecular Nutrition and Food Research. From the year 2000 Dr. Ho has been an honorary professor at universities in China. Currently he is an honorary professor at the China Agricultural University in Beijing.
Awards
IFT Stephen S. Chang Award for Lipid or Flavor Science:  Institute of Food Technologists
Board of Trustees Award for Excellence in Research at Rutgers, The State University of New Jersey: Rutgers University
Cited as “Highly Cited Researcher” in Agricultural Sciences: Institute for Scientific Information
Spotlight Award for Research Excellence: Cook College, Rutgers University
Fellow Award:  Agricultural and Food Chemistry Division, American Chemical Society
American Chemical Society Newsmaker for Research in an ACS Journal Award
Distinguished Service Award:  Agricultural and Food Chemistry Division, American Chemical Society
Platinum Award:  Agricultural and Food Chemistry Division, American Chemical Society, 1994 & 1995
PublicationsDr. Wong is widely published having written over 334 publications in scientific and medical journals. He has specialized in nutraceutical discovery and development including the unique properties of the noni plant. The following is a list of publications Dr. Ho has published which contribute to noni research.
Wang, Mingfu; Kikuzaki, Hiroe; Csiszar, Katalin; Boyd, Charles D.; Maunakea, Alika; Fong, Sheri F. T.; Ghai, Geetha; Rosen, Robert T.; Nakatani, Nobuji; Ho, Chi-Tang. Novel trisaccharide fatty acid ester identified from the fruits of Morinda citrifolia (Noni). Journal of Agricultural and Food Chemistry 1999, 47, 4880−4882.
Wang, Mingfu; Kikuzaki, Hiroe; Jin, Yi; Nakatani, Nobuji; Zhu, Nanqun; Csiszar, Katalin; Boyd, Charles D.; Rosen, Robert T.; Ghai, Geetha; Ho, Chi-Tang. Novel glycosides from noni (Morinda citrifolia). Journal of Natural Products 2000, 63, 1182−1183.
Sang, Shengmin; He, Kan; Liu, Guangming; Zhu, Nanqun; Wang, Mingfu; Jhoo, Jin-woo; Zheng, Qunyi; Dong, Zigang; Ghai, Geetha; Rosen, Robert T.; Ho, Chi-Tang. Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.). Tetrahedron Letters 2001, 42, 1823−1825.
Sang, Shengmin; He, Kan; Liu, Guangming; Zhu, Nanqun; Cheng, Xiaofang; Wang, Mingfu; Zheng; Qunyi; Dong, Zigang; Ghai, Geetha; Rosen, Robert T.; Ho, Chi-Tang. A new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of Morinda citrifolia L. Organic Letters 2001, 3, 1307−1309.
Sang, Shengmin; Cheng, Xiaofeng; Zhu, Nanqun; Wang, Mingfu; Jhoo, Jin-Woo; Stark, Ruth E.; Badmaev, Vladimir; Ghai, Geetha; Rosen, Robert T.; Ho, Chi-Tang. Iridoid glycosides from the leaves of Morinda citrifolia. Journal of Natural Products 2001, 64, 799−800.
Liu, Guangming; Bode, Ann; Ma, Wei-Ya; Sang, Shengmin; Ho, Chi-Tang; Dong, Zigang. Two novel glycosides from the fruits of Morinda citrifolia (Noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line. Cancer Research 2001 61, 5749−5756.
Sang, Shengmin; Liu, Guangming; He, Kan; Zhu, Nanqun; Dong, Zigang; Zheng, Qunyi; Rosen, Robert T.; Ho, Chi-Tang. New unusual iridoids from the leaves of noni (Morinda citrifolia L.) show inhibitory effect on ultraviolet B-induced transcriptional Activator Protein-1 (AP-1) activity. Bioorganic and Medicinal Chemistry 2003, 11, 2499−2502.
Noni ResearchDr. Ho’s research is related to the studying of noni. He has identified chemical components of noni fruit, leaves, and roots.



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